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Many factors lead to a frustrating cycle of weight gain and weight loss – but the driving force can be fatty cells that hold a Memory of obesity.
This is according to a recent study that was first published in Nature magazine last fall.
Researchers say that fat cells affect abnormal metabolic paths in the body long after they have shedding pounds, which could be more likely that people will regret weight.
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Findings of study
A team of Swiss scientists was curious whether Re -weight After weight loss is a consequence of “metabolic memory”, where the body remembers and tries to return to its former obesity state.
Many factors lead to a frustrating cycle of weight gain and weight loss – but the driving force can be fatty cells that keep the memory of obesity. (East)
They analyzed chemical markers on fat cells in mice that were fed with a high fat diet. Then, when the mice fed only a standard meal, researchers analyzed their fat after they lost weight, according to the study.
Tim then compared these patterns with a group of lean mice that was fed a Standard meal To see if chemical markers on fat cells are associated with unhealthy changes in the body.
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High -shaped mice still had unhealthy changes in their metabolism after losing weight, including more difficulty in regulating sugar metabolism, more inflammation and abnormal fat storage.
The mice that were previously obese were gained faster than the control group after eating a high fat diet-what suggests continuously diminishing metabolism after weight lossThe researchers discovered.
The mice that were previously obese were given to weight faster than the control group after eating a high fat diet-which suggests continuous damage to metabolism after losing weight. (East)
The study also studied human patterns, analyzing that genes in fatty cells can lead to unhealthy changes in the body as in mice.
Researchers analyzed the fatty tissues of the participants before and after undergoing bariatric surgery, comparing them to the fat cells of lean individuals who did not have the history of obesity.
“This recent research suggests that after someone loses weight, their fat cells do not return completely” normal “.
In obese individuals, the genes from fat cells continued to act abnormally in the body, which, two years after losing weight after losing weight, led to more inflammation and metabolic problems.
One study limit is that she watched only one type of fat cells. More research is needed to determine whether other cells or tissues in the body also keep the memory of overweight, researchers admitted.
The ‘complex blend’ of the factor
Fat cells really have a memory of obese, which can make it easier to return to weight and remain in a state that promotes inflammation and metabolic questions, confirmed Gretchen Zimmermann, a registered dietitian and vice president of the clinical strategy in Vid Health, a virtual obese provider. (Was not part of the study.)
“This recent study suggests that after someone loses weight, their fat cells are not returning completely” normal, “Zimmermann told Fox News Digital.
Researchers analyzed the fatty tissues of the participants before and after undergoing bariatric surgery, comparing them to the fat cells of lean individuals who did not have the history of obesity. (East)
But while biology plays a critical role in obesity, not everything, she warned.
“A complex blend of genetics, biology, environment, psychology, medicines and social determinants are obesity, “Zimmermann said.
“Continue to move, eat the right food and build muscle.”
Healthy habits can be opposed to the genetics that promote weight gain.
Ideally, an expert said, it involves a combination physical activity (including power training), sufficient amount of protein and fiber, and phytonutrients from plants that are contrary to oxidative stress and chronic inflammation, Zimmermann states.
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“Continue to move, eat the right food and build muscle,” she said.
“These behaviors reduce inflammation, improve blood sugar control, contribute to a healthy microbioma and protect metabolism – even if the weight does not fall much or remain the same.”
Healthy habits can confront genetics that promote weight gain, researchers say. (East)
For some, however, a fundamental question may lie Epigeneticswhich includes how a person’s behavior and the surrounding environment affect how genes work in the body, according to centers for the control and prevention of the disease.
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“Obesity is a chronic relapsing condition that has an epigenetic cause,” Fox News Digital, Dr. Caroline Apovian, a professor of medicine at the Harvard Medicine and co-Director of the Weight Management Center in Brigham and a women’s hospital.
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People who are more prone to calorie storage may harder to lose weight and keep it Diet and exerciseCompared to those who may have easier time, according to Apovian, who was not involved in the studio.
Fox News Digital addressed the study authors for comment.
